Treating disorders of the neonatal central nervous system: pharmacokinetic and pharmacodynamic considerations with a focus on antiepileptics
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چکیده
منابع مشابه
O 14: Differentiating Demyelinating Disorders of the Central Nervous System – a Focus on Multiple Sclerosis and Neuromyelitis-Optica Spectrum Disorders
Significant advances have been made in diagnosis and therapy of demyelinating disorders of the central nervous system. The most common entities of this disorders in adults – multiple sclerosis and neuromyelitis optica were initially thought to be different phenotypes of more or less the same disease. During the last ten years, this view was subsequently changed and the term neuromyelitis ...
متن کاملo 14: differentiating demyelinating disorders of the central nervous system – a focus on multiple sclerosis and neuromyelitis-optica spectrum disorders
significant advances have been made in diagnosis and therapy of demyelinating disorders of the central nervous system. the most common entities of this disorders in adults – multiple sclerosis and neuromyelitis optica were initially thought to be different phenotypes of more or less the same disease. during the last ten years, this view was subsequently changed and the term neuromyelitis optica...
متن کاملPharmacokinetic and pharmacodynamic considerations
in antimalarial dose optimization 2 3 NJ White 4 5 Mahidol-Oxford Tropical Medicine Research Unit, 6 Faculty of Tropical Medicine, Mahidol University, 7 Bangkok, Thailand. 8 9 Centre for Tropical Medicine, Churchill Hospital, 10 Oxford University, Oxford, United Kingdom 11 12 13 14 15 16 17 Correspondence: 18 Prof NJ White 19 Mahidol-Oxford Research Unit, 20 Faculty of Tropical Medicine, 21 Mah...
متن کاملPHArmACoKINeTIC AND PHArmACoDyNAmIC CoNSIDerATIoNS
INTroDuCTIoN Intramammary infection (mastitis) is the most common reason for the use of antimicrobials in dairy cows (Mitchell et al. 1998; Grave et al. 1999). Antimicrobials have been used to treat mastitis for more than fifty years, but consensus about the most efficient, safe, and economical treatment is still lacking. The concept of evidence-based medicine has been introduced to veterinary ...
متن کاملPharmacokinetic and pharmacodynamic interactions between antiepileptics and antidepressants.
INTRODUCTION Antiepileptic-antidepressant combinations are frequently used by clinicians; their pharmacokinetic (PK) and pharmacodynamic (PD) drug interactions (DIs) have not been well studied but are frequently likely to be clinically relevant. AREAS COVERED This article provides a comprehensive review of PK DIs between antiepileptics and antidepressants. In the absence of PD DI studies, PD ...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2015
ISSN: 0306-5251
DOI: 10.1111/bcp.12753